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Sumycin Prescribing Information

Sumycin is the brand name of a medication which caused by the generic name of tetracycline. Basically, Sumycin is a type of tetracycline antibiotic which is used to treat various bacterial infections. It works on the principal of obstructing and stopping down the production and spreading of the nutrients which are needed by the bacteria to flourish.

Hence, by restricting the growth of the bacteria in the affected parts, Sumycin tends to enhance the defense mechanism of the metabolism of our body and hence, protects our body from this kind of bacterial infections.

Apart from the usual bacterial infections, antibiotic also prevents and fights the symptoms of bronchitis, stomach ulcer, skin diseases, liver and kidney diseases as well as bacterial itches.

Sumycin tablets

Uses of Sumycin

Here are some of the uses of Sumycin:

  • Bacterial Infections: Medicine is effective against a wide range of bacterial infections caused by susceptible microorganisms. It can be used to treat infections in different parts of the body, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and more.
  • Acne: Tetracycline antibiotics like Sumycin are sometimes prescribed to treat moderate to severe cases of acne. They help reduce the growth of bacteria on the skin and can also have anti-inflammatory effects.
  • Rosacea: Tetracycline antibiotics can also be used to manage the symptoms of rosacea, a skin condition that causes redness and visible blood vessels on the face. They help control inflammation and reduce the appearance of symptoms.
  • Lyme Disease: Sumycin can be used to treat early stages of Lyme disease, which is a bacterial infection transmitted by ticks. It's important to note that other antibiotics may also be used depending on the specific situation.
  • Mycoplasma Infections: Tetracyclines are sometimes used to treat infections caused by Mycoplasma bacteria, such as walking pneumonia (Mycoplasma pneumoniae infections).
  • Chlamydia: Antibiotic can be used to treat certain sexually transmitted infections, such as chlamydia. However, other antibiotics like azithromycin or doxycycline are often preferred for treating these infections.
  • Gastrointestinal Infections: Tetracyclines can be used to treat certain gastrointestinal infections caused by bacteria such as Helicobacter pylori, which is associated with conditions like peptic ulcers.
  • Rickettsial Infections: Tetracyclines are effective against rickettsial infections, which are caused by bacteria like Rickettsia and can lead to diseases like Rocky Mountain spotted fever and typhus.

Dosage

The appropriate dosage of Sumycin can vary depending on the specific condition being treated, the severity of the infection, the patient's age, weight, and other factors. Dosage recommendations should always be determined by a qualified healthcare professional. However, I can provide you with some general dosage information for tetracycline:

Bacterial Infections:

  • Adults: Typically, the initial dose is around 500 mg to 1 g per day, divided into 2 to 4 doses. The dosage can be adjusted based on the response to treatment.
  • Children: The dosage for children is based on their weight, usually ranging from 25 to 50 mg per kg of body weight per day, divided into multiple doses.

Acne:

  • The typical dosage for acne treatment is lower than that for bacterial infections. It can range from 250 mg to 500 mg per day, divided into 2 doses.

Other Conditions:

  • Dosages for other conditions such as rosacea, Mycoplasma infections, and gastrointestinal infections can vary. Your healthcare provider will determine the appropriate dosage based on the specific condition being treated.

Tetracycline antibiotics should usually be taken on an empty stomach, at least 1 hour before or 2 hours after meals. This is because certain foods, as well as dairy products and antacids, can interfere with the absorption of the medication.

Additionally, it's crucial to complete the full course of antibiotics, even if you start feeling better before the course is finished. Stopping antibiotics prematurely can lead to incomplete treatment and the development of antibiotic-resistant bacteria.

Side Effects of Sumycin

Sumycin is generally well-tolerated, but like all medications, it can have potential side effects. Not everyone will experience these side effects, and their severity can vary. It's important to note that if you're prescribed Sumycin, your healthcare provider has determined that the benefits outweigh the potential risks. Here are some common and less common side effects:

Common Side Effects

  • Upset stomach
  • Nausea and vomiting
  • Diarrhea
  • Loss of appetite
  • Sensitivity to sunlight (increased risk of sunburn)
  • Changes in skin color or texture
  • Vaginal itching or discharge (in females)

Less Common or Serious Side Effects

  • Allergic reactions (rash, itching, swelling of the face, lips, or tongue)
  • Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
  • Tooth discoloration and enamel hypoplasia (more common in children)
  • Bone growth suppression (in children)
  • Liver problems (yellowing of the skin or eyes, dark urine, abdominal pain)
  • Kidney problems (changes in urination, swelling)
  • Blood disorders (anemia, low platelets, low white blood cell count)
  • Intracranial hypertension (increased pressure inside the skull, causing headaches and vision changes)

Interaction with other drugs

Sumycin can interact with various other drugs and substances, potentially affecting their effectiveness or increasing the risk of side effects. It's important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Sumycin. Here are some notable drug interactions:

  • Antacids and Dairy Products: Calcium-containing antacids, magnesium-containing antacids, and dairy products can bind to tetracycline and reduce its absorption. To avoid this interaction, take tetracycline at least 2 hours before or 2 hours after consuming these products.
  • Iron Supplements: Iron supplements can interfere with the absorption of tetracycline. Similar to antacids, it's advisable to take tetracycline a few hours before or after taking iron supplements.
  • Other Antibiotics: Tetracycline should not be used simultaneously with other antibiotics like penicillins, cephalosporins, and fluoroquinolones, as they can affect each other's efficacy.
  • Blood Thinners (Warfarin): Tetracycline may increase the effects of blood thinners like warfarin, potentially leading to an increased risk of bleeding. Regular monitoring of blood clotting times may be necessary.
  • Isotretinoin: Using tetracycline with isotretinoin (used to treat severe acne) can increase the risk of a condition called pseudotumor cerebri (intracranial hypertension).
  • Oral Contraceptives: Tetracycline can reduce the effectiveness of hormonal birth control methods like oral contraceptives. It's recommended to use additional forms of contraception while taking tetracycline.
  • Methotrexate: Tetracycline may increase the levels of methotrexate in the body, potentially leading to toxic effects. Close monitoring of methotrexate levels is advised.
  • Retinoids: Concurrent use of tetracycline and retinoids (e.g., isotretinoin, acitretin) can increase the risk of intracranial hypertension.
  • Digoxin: Tetracycline can increase the levels of digoxin in the body, which could lead to digoxin toxicity.
  • Anticoagulants and Antiplatelet Drugs: Tetracycline may increase the risk of bleeding when taken with anticoagulants (e.g., heparin, enoxaparin) or antiplatelet drugs (e.g., aspirin, clopidogrel).
  • Antidiabetic Medications: Tetracycline may affect blood sugar levels and require adjustments to antidiabetic medications.

What to avoid while on Sumycin

When taking Sumycin, there are several things you should avoid to ensure the medication's effectiveness and minimize the risk of side effects. Here are some important things to avoid:

  • Dairy Products: Dairy products, such as milk, cheese, and yogurt, contain calcium, which can bind to tetracycline and reduce its absorption. To avoid this interaction, it's recommended to separate your tetracycline dose from dairy products by at least 2 hours.
  • Antacids and Supplements: Avoid taking calcium-containing antacids, magnesium-containing antacids, and iron supplements at the same time as Sumycin. These can also interfere with the absorption of tetracycline. Take these products a few hours before or after taking this drug.
  • Sun Exposure: Tetracycline antibiotics, including Sumycin, can increase your skin's sensitivity to sunlight. Avoid prolonged sun exposure and use sunscreen, protective clothing, and sunglasses when outdoors. This can help prevent sunburn and skin damage.
  • Alcohol: While there is no direct interaction between tetracycline and alcohol, alcohol consumption can affect your immune system and potentially interfere with your body's ability to fight infections. Additionally, alcohol can have other negative health effects, so it's generally recommended to avoid excessive alcohol consumption while on any medication.
  • Other Medications: Inform your healthcare provider about all medications you are taking, including over-the-counter medications, herbal supplements, and vitamins. Some medications can interact with Sumycin and affect its effectiveness or increase the risk of side effects.
  • High-Iron Foods: Foods that are high in iron, such as red meat, can also interfere with the absorption of tetracycline. It's a good idea to separate your tetracycline dose from high-iron foods by a few hours.
  • Other Antibiotics: Avoid taking other antibiotics simultaneously with Sumycin unless specifically directed by your healthcare provider. Certain antibiotics can interact with each other and affect their efficacy.
  • Pregnancy and Breastfeeding: Sumycin should be used with caution during pregnancy, especially in the second and third trimesters, as it can affect the developing teeth and bones of the fetus. It's generally not recommended during breastfeeding as well. Consult your healthcare provider if you are pregnant or breastfeeding.
  • Driving and Operating Machinery: Some people may experience dizziness, lightheadedness, or blurred vision as side effects of Sumycin. If you experience these effects, it's best to avoid driving or operating heavy machinery until you know how the medication affects you.

Contraindications of Sumycin

Contraindications are specific situations or conditions in which a medication like Sumycin should not be used due to the potential risks outweighing the benefits. Here are some contraindications for using:

  • Allergy to Tetracyclines: If you have a known allergy to tetracycline antibiotics, including Sumycin, you should not take this medication.
  • Pregnancy: Sumycin is generally contraindicated during pregnancy, especially in the second and third trimesters. Tetracyclines can affect the development of the baby's teeth and bones.
  • Breastfeeding: Tetracyclines, including Sumycin, can be excreted in breast milk and may have adverse effects on the nursing infant's teeth and bone development. Therefore, it's usually not recommended during breastfeeding.
  • Children Under 8 Years Old: Tetracyclines can cause tooth discoloration and enamel hypoplasia (underdevelopment) in developing teeth. Therefore, they are generally not recommended for children under the age of 8.
  • Severe Liver or Kidney Dysfunction: Individuals with severe liver or kidney impairment may experience decreased clearance of tetracycline antibiotics, leading to potential toxicity. Sumycin should be used with caution or avoided in such cases.
  • Lupus: There have been reports of tetracyclines exacerbating symptoms of systemic lupus erythematosus (SLE), an autoimmune disease. Therefore, tetracycline use should be approached cautiously in individuals with lupus.
  • Myasthenia Gravis: Tetracyclines may worsen muscle weakness in people with myasthenia gravis, a neuromuscular disorder.
  • Porphyria: Tetracyclines can trigger attacks of acute porphyria, a group of rare inherited disorders that affect the nervous system or skin.
  • Isotretinoin Use: Concurrent use of tetracyclines and isotretinoin (used to treat severe acne) can increase the risk of a condition called pseudotumor cerebri (intracranial hypertension).
  • Use of Certain Retinoids: The combination of tetracycline antibiotics and certain retinoid medications can increase the risk of intracranial hypertension.

Pregnancy and Sumycin

Sumycin is generally not recommended during pregnancy, especially during the second and third trimesters, due to the potential risks it poses to the developing fetus. Tetracycline antibiotics, including Sumycin, can have adverse effects on fetal bone and teeth development.

The use of tetracyclines during pregnancy, particularly after the fourth month, can result in a condition known as "discolored teeth" or dental enamel hypoplasia. This can lead to permanent tooth discoloration and weakened enamel in the child's later years. Tetracyclines can also affect bone growth and development.

Given these potential risks, healthcare providers typically avoid prescribing tetracycline antibiotics to pregnant women, especially for non-life-threatening conditions. If a bacterial infection needs to be treated during pregnancy, alternative antibiotics that are considered safer for the developing fetus may be used.

If you are pregnant or planning to become pregnant and have been prescribed Sumycin or any other medication, it's crucial to discuss your situation with your healthcare provider. They will consider the specific risks and benefits for your condition and guide you towards the most appropriate treatment options. It's important to communicate openly with your healthcare provider to ensure the well-being of both you and your baby.

Drug Uses

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