Cefaclor Prescribing Information

This medicine is sold under the brand name Ceclor. It is a cephalosporin antibiotic of the second generation. It treats a wide variety of bacterial infections. It kills the bacteria by interfering with the formation of the bacteria`s cell wall. Once the wall is ruptured it results in the death of the bacteria. It belongs to the antibiotic group known as cephalosporins.

Cefaclor is a cephalosporin antibiotic used to treat bacterial infections of lungs, ear, throat, and urinary tract.

Mechanism of action (MOA)

Cefaclor works by blocking the bacterial cell wall and it binds to different proteins than those of penicillin. Rapid cell wall synthesis occurs when the organisms are actively multiplying. Therefore it is non toxic to man. The peptidoglycan strands in the bacterial cell wall. It interferes with the formation of bacterial cell wall while it’s still growing. It ruptures because of weakening of cell wall.

Uses of Cefaclor

It is used to treat pneumonia and infections of the ear, lung, skin, throat, and urinary tract. The Cefaclor works similar to penicillin's. It can also be used to fight the gram negative and gram positive bacteria organism.

  • Septicaemia
  • Pneumonia
  • Meningitis
  • Peritonitis
  • Biliary tract infections
  • Urinary tract infections
  • Otitis media
  • Lower respiratory tract infections
  • Pharyngitis
  • Tonsillitis
  • Skin structure infections

It can treat all bacterial infection and it doesn’t treat viral infections like flu.

Dosage and Administration

The tablet should be taken with a glass of water preferably after taking your meals or after 30 minutes of taking the meal. The usual adult dose is 0.5 – 1.0 g 8 hourly. The dose should be given in accordance to prescription. If the medicine is in liquid form please shake the bottle before you use it. You can store it in a cool place but do not freeze it.

Side Effects of Cefaclor

Like all medicines even Cefaclor has many side effects. However, it may not be relevant to all the patients. Some patients may or may not have any side effects. If in case you see any new symptoms after using this medicine, talk to your doctor immediately. Some of the common symptoms are

  • Headache
  • Mild diarrhea
  • Nausea
  • Sinus infection
  • Tiredness
  • Vomiting.

Apart from these common side effects, there can be various severe side effects as well. Get immediate medical help for the below symptoms.

  • Rash
  • Fever
  • Bloody stool
  • Hives
  • Unable to breathe
  • Swelling of the face, tongue or mouth
  • Irregular bowel movement
  • Vaginal discharge
  • Severe diarrhea
  • Stomach pain

Precaution and Warning

Some medicines are harmful when taken with other medicine. Therefore please consult your doctor regarding any medicines you are taking beforehand. Also give your full family and personal history. Some allergies may trigger due to taking two medicines together. If you already have allergic reaction to any medicine let your doctor know.

Some patients may develop hypersensitivity reactions following cefaclor, please stop the medication immediately and get in touch with your doctor.

If you had any surgery, tell your physician about it before taking cefaclor. Do not discontinue the medication abruptly without consulting doctor.

Contraindications of Cefaclor

This medicine is not effective for treating viral infections. This medicine is not for regular use without the doctor's advice. If this medicine is used repeatedly for a long term, it can cause a second infection. If you have any allergy to this medicine or if you are taking any prescription, non-prescription, or herbal medicine, then inform your doctor about the same. If you have a liver, kidney, phenylketonuria, or blood clotting disorder, then this medicine can cause severe side effects. Medicines such as probenecid and warfarin can increase the side effects of this medicine. You should check with your health care provider if you are using any medicine and when it will be safe to start or stop any medicine. Any changes in the dose of any medicine should also be discussed prior to making the changes. Follow the instructions on the prescription or as suggested by the doctor. It can be taken with or without food and you should chew it, before swallowing the medicine. Make sure that you take this medicine at the same time every day to increase the effectiveness of the medicine. The symptoms of the infection may improve before the full course of the medicine is over. It is important that you continue to use the medicine and complete the full course. Failing to do so can repeat the infection. Overdose of this medicine can be harmful and life threatening. It can also, give false results in certain tests, hence let the doctor know that you are using the medicine.

Pregnancy and Cefaclor

You should discuss the benefits and risks of using this medicine during pregnancy. This medicine can pass through the breast milk to the nursing child and may harm the child.

It is not entirely known if it affects pregnant women. Ask your doctor regarding this and if gives you a thumps up then only take it. It may secrete into milk in small quantities that does not harm anybody.

Drug Interaction

Some drugs like warfarin and probenecid should not be used while taking cefaclor as it may alter the course of action. Also some false negative test of glucose in the urine may come like benedict’s.

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