Minomycin Prescribing Information

Minocycline Hydrochloride belongs to the class of tetracycline antibiotics. It is among the most lipid-soluble of all the tetracycline antibiotics and is also a bacteriostatic antibiotic. It provides the greatest penetration inside the brain and the prostrate, along with the greatest amount of side-effects affecting the Central Nervous System (CNS), like vertigo. It is usually orally administered. The drug isn't naturally found, but synthesized from natural tetracycline antibiotics. The trade name of minocycline hydrochloride is Minocin.

Composition of Minocycline Hydrochloride

Minocycline hydrochloride is a semi-synthetic antibiotic belonging to the class of tetracycline. The tablets are orally administered by the patient. The inactive ingredients in these tablets are:

  • Carnauba wax NF
  • Colloidal silicon dioxide NF
  • Magnesium stearate NF
  • Hypromellose type 2910 USP
  • Lactose monohydrate NF

Uses of Minocycline Hydrochloride

This tetracycline antibiotic is used for the treatment of many bacterial infections. It helps in treating respiratory infections, urinary tract infections, tick fever, severe acne, gonorrhoea, Chlamydia, skin infections and many more. It helps in eliminating the growth of the bacteria inside the body. Viral infections like flue and common cold cannot be treated with the help of this medication.

Side-effects of Minocycline Hydrochloride

Using Minocycline Hydrochloride can result in various side-effects. Some of these side-effects are as follows:

Major side-effects:

  • Tarry and black stools
  • Peeling, loosening, or blistering of the skin
  • Blood present in the stools and urine
  • Double or blurred vision
  • Presence of a bulging soft spot (head) in an infant
  • Chest pain, gradually moving to the neck, left arm, or shoulder
  • Diarrhoea
  • Confusion
  • Light-headedness or dizziness
  • Fast heartbeat
  • Eye pain
  • General feeling of illness or discomfort
  • Itching, skin rash, or hives
  • General weakness or tiredness
  • Muscle or joint pain
  • Hive-like and large swelling on the eyelids, face, tongue, lips, hands, throat, feet, legs, or sex organs
  • Vomiting or nausea
  • Loss of appetite
  • Red skin lesions
  • Severe stomach pain
  • Severe headache
  • Ulcers, white spots, or sores in the mouth or lips
  • Unusual bruising or bleeding
  • Troubled breathing
  • Yellow skin and eyes
  • Pain in the upper right side of the abdomen or stomach

Minor side-effects:

  • Hearing loss
  • Difficulty while moving
  • Buzzing or ringing, or any unexplained noises heard in the ears
  • Welts or hives
  • Redness of the skin
  • Muscle stiffness
  • Unusual sleepiness or drowsiness
  • Discolouration of the teeth
  • Bloating
  • Indigestion
  • Increase in the sensitivity of the skin to sunlight
  • Severe sunburn

Contraindications of Minocycline Hydrochloride

There are certain conditions under which Minocycline Hydrochloride should not be prescribed to the patient. Some of these conditions are mentioned below:

  • Allergic reaction to tetracyclines
  • Clostridium Difficile Bacteria Related Colitis
  • Azotemia
  • Kidney disease
  • Problems related to food passage through the food pipe
  • Pseudotumor Cerebri
  • Liver problems

Minocycline Hydrochloride and Pregnancy

There have been evidences of embryo and fetotoxicity along with toxic effects to the skeletal formation. Though there has been no controlled data collected on human subjects, it is best advised not to not take Minocycline Hydrochloride at the time of pregnancy.

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